Adwistadine

Indication :

Treatment of coronary artery disease

Symptomatic treatment of chronic stable angina pectoris in coronary artery disease adults with normal sinus rhythm. Ivabradine is indicated:

- in adults unable to tolerate or with a contra-indication to the use of beta-blockers

- or in combination with beta-blockers in patients inadequately controlled with an optimal beta-blocker dose and whose heart rate is > 60 bpm.

Treatment of chronic heart failure

Ivabradine is indicated in chronic heart failure NYHA II to IV class with systolic dysfunction, in patients in sinus rhythm and whose heart rate is ≥ 75 bpm, in combination with standard therapy including beta-blocker therapy or when beta-blocker therapy is contraindicated or not tolerated

Composition :

Adwistadine 5 mg

One film-coated tablet contains 5 mg ivabradine (equivalent to 5.390 mg ivabradine as hydrochloride).

Adwistadine 7.5 mg

One Scored film-coated tablet contains 7.5 mg ivabradine (equivalent to 8.085 mg ivabradine as hydrochloride) List of excipients

Active ingredients:

Ivabradine Hydrochloride

Excipients:

Cellactose

Starch 1500

Colloidal silicon dioxide

Magnesium stearate

Coating ingredients:

Hypromellose (methocel E5)

Titanium Dioxide

PEG 6000

Purified Talc powder

Yellow iron oxide

Red iron oxide