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Adwiflam.(Sachet)

 


Composition:
Each 2 gm sachet contains 50mg Diclofenac Potassium in a powder form.

Properties:
Non steroidal anti-inflammatory drug with pronounced analgesic and antipyretic actions. Diclofenac is an inhibitor of cyclooxygenase and its potency is substantially greater than that of indomethacin, naproxen and several other NSAIDs. The mechanism of action of Diclofenac, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition.
Diclofenac is eliminated through metabolism and subsequent urinary and biliary excretion of
the glucuronide and the sulfate conjugates of the metabolites. Little or no free unchanged diclofenac is excreted in the urine. Approximately 65% of the dose is excreted in the urine.

Indications:
Adwiflam sachets is indicated as short term treatment (maximum 2 weeks) for the following acute conditions:
- Postoperative inflammation and pain (e.g. dental or orthopedic surgery )
- Acute musculoskeletal disorders (e.g. post-traumatic pain, sprains, strains, tendinitis, bursistis, acute painful shoulder or contusions)
- Primary dysmenorrhoea or adnexitis.
- Migraine attacks.
- Ear, nose or throat painful inflammations.
- Control of fever (along with the treatment of the underlying cause as fever is not an indication by itself.

Dosage Administration:
Contents of one sachet are to be dispersed in a half glass of natural water preferably before meals.
Dosage :
•Adults: One Adwiflam sachet is to be taken , 2-3 times daily in the conditions of severs pain or inflammations.
•Adolescents over 14 years of age and mild conditions, a dose ranging between 50 and 100 mg daily will generally be sufficient.
•In primary dysmenorrhoea, the daily dosage should be individually adjusted, and ranges generally between 50 to 150mg.
•Migraine: An initial dose of 50mg is recommended at the first sign of an attack. In cases where pain relief is inadequate approximately 2 hours after ingestion of the first dose a further dose of 50 mg may be taken.

Contra Indications:
In patients with known hypersensitivity to diclofenac.
In patients who have experienced asthma, urticaria, or allergic- type reactions after taking aspirin or other NSAIDs.

Precautions Warnings:
Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids.

Side Effects:
Gastrointestinal experiences including: abdominal pain, constipation, diarrhea, dyspepsia, flatulence, nausea, vomiting.
Anemia, dizziness, edema, elevated liver enzymes and headache.

Packing:
Box containing 10 sachets each of 2gm.

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