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Adwiflam 25mg Pediatric.(Suppositories)

 


Composition:
Each pediatric suppository contains 25mg Diclofenac Potassium.

Properties:
Non steroidal anti-inflammatory drug with pronounced analgesic and antipyretic actions. Diclofenac is an inhibitor of cyclooxygenase and its potency is substantially greater than that of indomethacin, naproxen and several other NSAIDs. The mechanism of action of Diclofenac, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition.
Diclofenac is eliminated through metabolism and subsequent urinary and biliary excretion of
the glucuronide and the sulfate conjugates of the metabolites. Little or no free unchanged diclofenac is excreted in the urine. Approximately 65% of the dose is excreted in the urine.

Indications:
- Fever.
- Tonsillitis.
- Pharyngitis.
- Otitis media.
- Post opertaive pain.
- Trauma.

Dosage Administration:
For chidren 1 to 12 years: 1 – 3 mg per Kg body-weight daily in divided doses.

Contra Indications:
In patients with known hypersensitivity to diclofenac.
In patients who have experienced asthma, urticaria, or allergic- type reactions after taking aspirin or other NSAIDs.

Precautions Warnings:
Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids.

Side Effects:
Gastrointestinal experiences including: abdominal pain, constipation, diarrhea, dyspepsia, flatulence, nausea, vomiting.

Packing:
Box containing 5 pediatric suppositories.

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