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Amadol.(Ampoules)

 


Composition:
Each 2ml Ampoule contains Tramadol Hcl 100 mg.

Properties:
Amadol (Tramadol HCl) has a dual mechanism of action within the CNS as it exerts agonistic properties at opiate receptors and interferes with the neurotransmitter reuptake of norepinephrine and serotonin.
It also binds weakly to µ opiate receptors, blocking the transmission of pain signals to the brain.

Indications:
Amadol is used for the relief of back pain, moderate pain, neuropathic pain, orthopedic pain, severe pain and surgical pain.

Dosage Administration:
By intramuscular injection or by intravenous injection (over 2-3 minutes) or by intravenous infusion 50-100mg every 4-6 hours.
For the treatment of moderate or severe pain, chronic conditions and cancer pain, the recommended dose is:
-Adults & adolescents (>16 years) 50-100 mg every 4-6 hours (not exceeding 400mg/day).
-Elderly patients: the maximum daily dose is 300mg given in divided doses.

Contra Indications:
Amadol should be used with caution on patients with or at risk of respiratory depression, patients with pre-existing seizure disorders, with G.I. diseases, with increased intracranial pressure or head trauma. Caution is needed in using Amadol with carbamazepine, quinidine, MAOI’s, phenothiazines, antidepressants, antipsychotics and general anaesthetics.

Precautions Warnings:
-Dose selection for an elderly patient should be cautions, reflecting the greater frequency of decreased hepatic, renal or cardiac function or presences of concomitant disease.
Pregnancyanlaction:
-Amadol is classified as pregnancy category C.
-Amadol is not recommended for obstetrical preoperative medication or for post delivery analgesia in nursing mothers. It should not be given to women prior to, or during labor unless the benefits outweigh the risks.
-Not recommended for use in breast feeding woman.

Side Effects:
CNS
Dizziness, vertigo headache, drowsiness, anxiety, agitation, tremors, euphoria, insomnia, visual impairment.
G.I.T:
Nausea, vomiting, constipation, diarrhea, dyspepsia, xerostomia, abdominal pain and anorexia.
Urinary:
Increased urinary frequency or urinary retention.
Cardiovascular:
Vasodilatation, hypotension or sinus tachycardia.
Dermatological:
Pruritis, rash and urticaria.

Packing:
Box containing 3 ampoules each of 2ml.

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