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Carprofen 5% Injection . (Injection)

 

Composition:
Each 1 ml contains:
Carprofen 50 mg.


Properties:
Long acting non-steroidal anti-inflammatory.
Mode of Action:Inhibition of cyclooxygenase is believed to be the mechanism of action for the anti-inflammatory effect of carprofen. Carprofen a COX2 selective NSAID.
Carprofen selectively inhibits cyclooxygenase 2 (COX-2) over cyclooxygenase 1 (COX-1).
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic effects and minimal risk for toxicity in animals.



Indications:
It is for use on dogs, cats, horses, ponies and cattle.
Carprofen is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
In horses and ponies it can be used for analgesic and anti-inflammatory action in musculo-skeletal properties.


Dosage Administration:
In cattle: 3 ml/100 kg/day as a single I/V or S/C injection.
In horses: 1.5 ml/100 kg/day as an I/V injection only as a single dose.
In dogs: 1 ml/10 kg once daily by SC route.


Precautions Warnings:
Carprofen should not be used in animals with known hypersensitivity or allergy to the drug.
Carprofen may interact with other drugs like aspirin and corticosteroids.
Combination with corticosteroids potentially increased ulcerogenic effect.
As with any NSAID, GI side-effects can be substantial, discontinue use if GI signs develop
Monitor liver enzymes of canine patients on chronic therapy.
Store below 30º C away form direct sun light and Keep out of the reach of children

Side Effects:
There have been occasional reports of stomach upset, ulcers, or diarrhea associated with giving carprofen to dogs.
More serious problems associated with carprofen include stomach ulcers, liver injury, and urinary tract problems.
Other rare side effects include blood cell suppression and seizures.


Withdrawal time:
For bovine edible tissues: 21 days.
Milk: shouldn’t be used for animals producing milk for human consumption


Packing:
25, 50 and 100 ml vials.

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